A tPSA test (Total Prostate-Specific Antigen) is a blood test that measures the total amount of a protein produced by the prostate gland.
It is used primarily for prostate cancer screening and monitoring prostate health. High levels of tPSA can indicate various prostate conditions, including prostate cancer, but also non-cancerous issues like an enlarged prostate (BPH) or prostatitis.
What the test is for
- Prostate cancer screening: It helps to identify men who may be at risk of prostate cancer.
- Prostate health monitoring: It is used to track prostate health over time.
What the results mean
- Elevated tPSA levels can indicate several conditions, not just cancer.
- Other conditions that can cause elevated tPSA include an enlarged prostate (benign prostatic hyperplasia or BPH) and inflammation of the prostate (prostatitis).
- A high tPSA level may suggest a need for further diagnostic tests, such as a prostate biopsy.


